(19)

(11)

EP 1 408 994 A2

(12)

(88) Date of publication A3: 13.09.2001 (43) Date of publication: 21.04.2004 Bulletin 2004/17 (21) Application number: 00957529.1 (22) Date of filing: 18.08.2000

(51) International Patent Classification (IPC)7: A61K 33/40, A61P 35/00 (86) International application number: PCT/US2000/022610 (87) International publication number: WO 2001/012205 (22.02.2001 Gazette 2001/08)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 18.08.1999 US 149429 P (71) Applicant: OXO Chemie AG 1701 Fribourg (CH)	(72) Inventors: KUHNE, Frederich W. Bangkok 10250 (TH) KODELJA, Vitam D-12167 Berlin (DE) (74) Representative: Olgemöller, Luitgard, Dr. et al Leonhard - Olgemöller - Fricke,Patentanwälte,Postfach 10 09 57 80083 München 80083 München (DE)