(19)

(11)

EP 1 409 040 A2

(12)

(88) Date of publication A3: 20.03.2003 (43) Date of publication: 21.04.2004 Bulletin 2004/17 (21) Application number: 02749940.9 (22) Date of filing: 27.06.2002

(51) International Patent Classification (IPC)7: A61M 1/00 (86) International application number: PCT/US2002/021945 (87) International publication number: WO 2003/002170 (09.01.2003 Gazette 2003/02)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 27.06.2001 US 301631 P (71) Applicant: Durect Corporation Cupertino, CA 95014 (US)	(72) Inventor: GILLIS, Edward, M. Cupertino, CA 95014 (US) (74) Representative: Ebner von Eschenbach, Jennifer  Ladas & Parry,Dachauerstrasse 37 80335 München 80335 München (DE)