(19)
(11) EP 1 412 483 A1

(12)

(43) Date of publication:
28.04.2004 Bulletin 2004/18

(21) Application number: 02764785.8

(22) Date of filing: 26.07.2002
(51) International Patent Classification (IPC)7: C12N 5/06, C12N 5/08, C12M 3/04, C12M 1/14, C12M 1/20, C12M 1/24, A61K 35/14
(86) International application number:
PCT/EP2002/008318
(87) International publication number:
WO 2003/012081 (13.02.2003 Gazette 2003/07)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 27.07.2001 EP 01118199

(71) Applicant: Merix Bioscience, Inc.
Durham,North Carolina 27704 (US)

(72) Inventors:
  • SCHULER, Gerold
    91080 Spardorf (DE)
  • THURNER-SCHULER, Beatrice
    91080 Spardorf (DE)
  • BERGER, Thomas
    91054 Erlangen (DE)

(74) Representative: Helbing, Jörg, Dr. et al
Postfach 10 22 41
50462 Köln
50462 Köln (DE)

   


(54) GENERATION OF FULLY MATURE AND STABLE DENDRITIC CELLS FROM LEUKAPHERESES PRODUCTS FOR CLINICAL APPLICATIONS