AKT AND REGULATION OF RA SYNOVIAL FIBROBLAST APOPTOSIS - Patent 1414500

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(11)

EP 1 414 500 A2

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(88)	Date of publication A3:
	04.03.2004

(43)	Date of publication:
	06.05.2004 Bulletin 2004/19

(21)	Application number: 02731374.1

(22)	Date of filing: 16.04.2002

(51)	International Patent Classification (IPC)⁷: A61K 48/00, C07H 21/00, C07H 21/02, C07H 21/04

(86)	International application number:
	PCT/US2002/011820

(87)	International publication number:
	WO 2002/083075 (24.10.2002 Gazette 2002/43)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
	Designated Extension States:
	AL LT LV MK RO SI

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Priority:

16.04.2001 US 283966 P

(71)	Applicant: UAB Research Foundation
	Birmingham, AL 35294-0111 (US)

(72)	Inventors:
	MOUNTZ, John, D. Birmingham, AL 35216 (US) ZHANG, Huang-Ge Birmingham, AL 35216 (US) XIE, Jin-Fu Birmingham, AL 35205 (US) LIANG, Xu Birmingham, AL 35205 (US) YANG, Pingar Birmingham, AL 35294-0007 (US) HSU, Hui-Chen Birmingham, AL, 35209 (US)

(74)	Representative: Williams, Richard Andrew Norman et al
	Hepworth Lawrence Bryer & BizleyMerlin HouseFalconry CourtBakers Lane Epping, Essex CM16 5DQ Epping, Essex CM16 5DQ (GB)

(54)	AKT AND REGULATION OF RA SYNOVIAL FIBROBLAST APOPTOSIS