(19)
(11) EP 1 414 804 A1

(12)

(43) Date of publication:
06.05.2004 Bulletin 2004/19

(21) Application number: 00973682.8

(22) Date of filing: 20.10.2000
(51) International Patent Classification (IPC)7C07D 231/54, C07D 401/12, C07D 409/12, A61K 31/416, A61P 35/00
(86) International application number:
PCT/US2000/028952
(87) International publication number:
WO 2002/034721 (02.05.2002 Gazette 2002/18)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(71) Applicant: Bristol-Myers Squibb Pharma Company
Princeton,New Jersey 08543-4000 (US)

(72) Inventors:
  • NUGIEL, David, A.
    Cherry Hill, NJ 08003 (US)
  • CARINI, David, J.
    Wilmington, DE 19803 (US)
  • DI MEO, Susan, V.
    Wilmington, DE 19809 (US)
  • VIDWANS, Anup
    Wilmington, DE 19808-3406 (US)
  • YUE, Eddy, W.
    Landenberg, PA 19350 (US)

(74) Representative: Wittop Koning, Tom Hugo 
Exter Polak & Charlouis B.V.,P.O. Box 3241
2280 GE Rijswijk
2280 GE Rijswijk (NL)

   


(54) ACYLSEMICARBAZIDES AND THEIR USE AS CYCLIN DEPENDENT KINASE (CDK) INHIBITORS