(19)
(11) EP 1 421 097 A2

(12)

(88) Date of publication A3:
22.05.2003

(43) Date of publication:
26.05.2004 Bulletin 2004/22

(21) Application number: 02759231.0

(22) Date of filing: 31.07.2002
(51) International Patent Classification (IPC)7C07H 21/04, C12N 15/74, C12N 1/20, C12N 1/14, C12N 1/16, C12N 5/00, C12N 5/02, C12N 5/04, C12N 5/10, C12N 1/00, C12P 21/06, C12Q 1/68
(86) International application number:
PCT/US2002/024310
(87) International publication number:
WO 2003/014297 (20.02.2003 Gazette 2003/08)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 06.08.2001 US 310385 P
17.10.2001 WO PCT/US01/32354
10.05.2002 US 379866 P

(71) Applicant: Cubist Pharmaceuticals, Inc.
Lexington, MA 02421 (US)

(72) Inventors:
  • MIAO, Vivian, Pak, Woon
    Surrey, British Columbia V4P 2B7 (CA)
  • BRIAN, Paul
    Waltham, MA 02451 (US)
  • BALTZ, Richard, H.
    Lincoln, MA 01773 (US)
  • COEFFET-LEGAL, Marie Francoise
    Arlington, MA 02474 (US)

(74) Representative: VOSSIUS & PARTNER 
Siebertstrasse 4
81675 München
81675 München (DE)

   


(54) COMPOSITIONS AND METHODS RELATING TO THE DAPTOMYCIN BIOSYNTHETIC GENE CLUSTER