(19)

(11)

EP 1 421 102 A2

(12)

(88) Date of publication A3: 25.03.2004 (43) Date of publication: 26.05.2004 Bulletin 2004/22 (21) Application number: 02750841.5 (22) Date of filing: 18.07.2002

(51) International Patent Classification (IPC)7: C07K 1/00, C07K 14/605 (86) International application number: PCT/DK2002/000501 (87) International publication number: WO 2003/010185 (06.02.2003 Gazette 2003/06)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 24.07.2001 DK 200101140 (71) Applicant: NOVO NORDISK A/S 2880 Bagsvaerd (DK)	(72) Inventors: BALSCHMIDT, Per DK-3060 Esperg rde (DK) DIERS, Ivan DK-3500 V rl se (DK) EGEL-MITANI, Michi DK-2950 Vedb k (DK) MARKUSSEN, Jan DK-2730 Herlev (DK) H EG-JENSEN, Thomas DK-2930 Klampenborg (DK) (74) Representative: Secher, Anne et al c/o Novo Nordisk A/SNovo Allé 2880 Bagsvaerd 2880 Bagsvaerd (DK)