(19)
(11) EP 1 427 366 A2

(12)

(88) Date of publication A3:
20.11.2003

(43) Date of publication:
16.06.2004 Bulletin 2004/25

(21) Application number: 02766096.8

(22) Date of filing: 21.08.2002
(51) International Patent Classification (IPC)7: A61F 6/06, A61F 13/02, A61K 47/30
(86) International application number:
PCT/US2002/027027
(87) International publication number:
WO 2003/020210 (13.03.2003 Gazette 2003/11)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 29.08.2001 US 315877 P

(71) Applicant: UMD, Inc.
Cincinnati, OH 45242 (US)

(72) Inventors:
  • PAULETTI, Giovanni, M.
    Loveland, OH 95140 (US)
  • LIU, James, H.
    Cincinnati, OH 45230 (US)
  • BENET, Leslie, Z.
    Belvedere, CA 94920 (US)
  • RITSCHEL, Wolfgang, A.
    Cincinnati, OH 45220 (US)

(74) Representative: Sexton, Jane Helen 
J.A. KEMP & CO.14 South SquareGray's Inn
London WC1R 5JJ
London WC1R 5JJ (GB)

   


(54) VAGINAL DELIVERY OF CHEMOTHERAPEUTIC AGENTS AND INHIBITORS OF MEMBRANE EFFLUX SYSTEMS FOR CANCER THERAPY