(19)
(11) EP 1 432 408 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
02.03.2011 Bulletin 2011/09

(45) Mention of the grant of the patent:
27.10.2010 Bulletin 2010/43

(21) Application number: 02774661.9

(22) Date of filing: 27.09.2002
(51) International Patent Classification (IPC): 
A61K 9/20(2006.01)
A61K 31/445(2006.01)
 A61K 31/435(2006.01)
(86) International application number:
PCT/EP2002/010890
(87) International publication number:
WO 2003/028705 (10.04.2003 Gazette 2003/15)

(54)

PHARMACEUTICAL COMPOSITIONS COMPRISING COLLOIDAL SILICON DIOXIDE

PHARMAZEUTISCHE ZUBEREITUNGEN ENTHALTEND KOLLOIDALES SILICIUMDIOXID

COMPOSITIONS PHARMACEUTIQUES A BASE DE DIOXYDE DE SILICIUM COLLOIDAL

(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
Designated Extension States:
RO SI

(30) Priority: 28.09.2001 GB 0123400

(43) Date of publication of application:
30.06.2004 Bulletin 2004/27

(60) Divisional application:
09177889.4 / 2193788

(73) Proprietors:
  • Novartis AG
    4056 Basel (CH)
    Designated Contracting States:
    BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR 
  • Novartis Pharma GmbH
    1230 Wien (AT)
    Designated Contracting States:
    AT 

(72) Inventors:
  • HAEBERLIN, Barbara
    CH-4142 Münchenstein (CH)
  • KRAMER, Andrea
    79276 Reute (DE)
  • HEUERDING, Silvia
    CH-4051 Basel (CH)

(74) Representative: de Weerd, Petrus G.W. et al
Novartis International AG Corporate Intellectual Property
4002 Basel
4002 Basel (CH)


(56) References cited: : 
EP-A- 1 145 711
 US-A- 6 004 973
   
  • NÜRNBERG E ET AL: "Coating of cellulose products with colloidal silicon dioxide. Investigations to improve tabletting behaviour using low dose tablets as an example" DRUGS MADE IN GERMANY, AULENDORF, DE, vol. 39, no. 3, 1996, pages 104-107, XP002902513 ISSN: 0012-6682
  • LINDEN R ET AL: "Response surface analysis applied to the preparation of tablets containing a high concentration of vegetable spray-dried extract." DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY. UNITED STATES APR 2000, vol. 26, no. 4, April 2000 (2000-04), pages 441-446, XP009006020 ISSN: 0363-9045
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).