(19)
(11) EP 1 434 782 A2

(12)

(88) Date of publication A3:
30.10.2003

(43) Date of publication:
07.07.2004 Bulletin 2004/28

(21) Application number: 02800432.3

(22) Date of filing: 01.10.2002
(51) International Patent Classification (IPC)7C07H 19/16, A61K 31/70, A61P 29/00
(86) International application number:
PCT/US2002/031383
(87) International publication number:
WO 2003/029264 (10.04.2003 Gazette 2003/15)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 01.10.2001 US 326517 P
24.05.2002 US 383200 P

(71) Applicant: University of Virginia Patent Foundation
Charlottesville, VA 22903-2442 (US)

(72) Inventors:
  • LINDEN, Joel, M.
    Charlottesville, VA 22903 (US)
  • RIEGER, Jayson, M.
    Charlottesville, VA 22911 (US)
  • MACDONALD, Timothy, L.
    Charlottesville, VA 22903 (US)
  • SULLIVAN, Gail, W.
    Charlottesville, VA 22903 (US)
  • MURPHREE, Lauren, Jean
    Earlysville, VA 22936 (US)
  • FIGLER, Robert, Alan
    Earlysville, VA 22936 (US)

(74) Representative: Lucas, Brian Ronald et al
Lucas & Co.135 Westhall Road
Warlingham,Surrey CR6 9HJ
Warlingham,Surrey CR6 9HJ (GB)

   


(54) 2-PROPYNYL ADENOSINE ANALOGS HAVING A2A AGONIST ACTIVITY AND COMPOSITIONS THEREOF