WORTMANNIN ANALOGS AND METHODS OF USING SAME

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EP 1 435 941 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	25.10.2006 Bulletin 2006/43

(45)	Mention of the grant of the patent:
	02.08.2006 Bulletin 2006/31

(21)	Application number: 02766286.5

(22)	Date of filing: 16.09.2002

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International Patent Classification (IPC):

A61K 31/352^(2006.01)
A61P 35/00^(2006.01)

C07D 311/94^(2006.01)

(86)	International application number:
	PCT/US2002/029365

(87)	International publication number:
	WO 2003/024183 (27.03.2003 Gazette 2003/13)

(54)	WORTMANNIN ANALOGS AND METHODS OF USING SAME WORTMANNINANALOGE UND VERFAHREN ZU DEREN VERWENDUNG ANALOGUES DE WORTMANNINE ET LEURS METHODES D'UTILISATION

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR

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Priority:

14.09.2001 US 322139 P
14.09.2001 US 322143 P

(43)	Date of publication of application:
	14.07.2004 Bulletin 2004/29

(60)	Divisional application:
	06010324.9 / 1686124

(73)	Proprietors:
	ARIZONA BOARD OF REGENTS on behalf of THE UNIVERSITY OF ARIZONA Tucson, AZ 85721-0151 (US) UNIVERSITY OF PITTSBURGH Pittsburgh, PA 15260-4002 (US)

(72)	Inventors:
	WIPF, Peter Pittsburgh, PA 15213 (US) POWIS, Garth Tucson, AZ 85750 (US)

(74)	Representative: Ouzman, Beverley Nicola Claire et al
	Murgitroyd & Company Scotland House 165-169 Scotland Street Glasgow G5 8PL Glasgow G5 8PL (GB)

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References cited: :

GB-A- 2 302 021

BRYAN H. NORMAN ET AL.: "stusies on the mechanism of phosphatidylinositol 3-kinase inhibition by wortmannin a. related analogues." JOURNAL OF MEDICINAL CHEMISTRY., vol. 39, no. 5, 1996, pages 1106-1111, XP002300056 USAMERICAN CHEMICAL SOCIETY. WASHINGTON.
VON HAEFLIGER W.: 'Selektive Funktionalisierung von Wortmannin mit Hilfe einer Furanring-Maskierung' HELVETICA CHIMICA ACTA vol. 58, no. 6, 1975, pages 1620 - 1628, XP002962871

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).