ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESILTLVFIROMKCYALTRBGCZEE....SK....................................*JDIM360 Ver 2.40 (30 Jan 2013) - 2999001/01436290CORRECTED EUROPEAN PATENT SPECIFICATIONB8B120131204W173deBibliographieenBibliographyfrBibliographieEP02754079.8200208272004032920081121enenen316093 P20010829US2013120420134920040714200429201309182013382013041820131204201349C07D 471/04 20060101AFI20030310BHEP C07D 519/00 20060101ALI20030310BHEP A61K 31/435 20060101ALI20030310BHEP deALKYNE-ARYL-NAPHTHYRIDIN-4(1H)-0NE DERIVATE ALS HEMMER VON PHOSPHODIESTERASE DES TYPS IVenALKYNE-ARYL-NAPHTHYRIDIN-4(1H)-0NE DERIVATIVES AS TYPE IV PHOSPHODIESTERASE INHIBITORfrDERIVES D'ALKYNE-ARYLE-NAPHTHYRIDINE-4-ONE (1H) TENANT LIEU D'INHIBITEURS DE PHOSPHODIESTERASE-4EP-A- 0 978 516WO-A-00/09504WO-A-99/07704MATSUURA A ET AL: "Substituted 1,8-Naphthyridin-281H)-ones as Selective Phosphodiesterase IV Inhibitors" BIOLOGICAL & PHARMACEUTICAL BULLETIN (OF JAPAN), PHARMACEUTICAL SOCIETY OF JAPAN, JP, vol. 17, no. 4, 1 April 1994 (1994-04-01), pages 498-503, XP002084207 ISSN: 0918-615810191086.7230567720101112GUAY, Daniel16711 Trans-Canada HighwayKirkland, Québec H9H 3L1CAGIRARD, Mario16711 Trans-Canada HighwayKirkland, Québec H9H 3L1CAHAMEL, Pierre16711 Trans-Canada HighwayKirkland, Québec H9H 3L1CALALIBERTE, Sebastien16711 Trans-Canada HighwayKirkland, Québec H9H 3L1CAFRIESEN, Richard16711 Trans-Canada HighwayKirkland, Québec H9H 3L1CAMerck Canada Inc.101240871MC 05116711 Trans-Canada HighwayKirkland QC H9H 3L1CABuchan, Gavin MacNicolet al100814197Merck Sharp & Dohme Limited European Patent Department Hertford RoadHoddesdon Hertfordshire EN11 9BUGBATBEBGCHCYCZDEDKEEESFIFRGBGRIEITLILUMCNLPTSESKTRAL20040329LT20040329LV20040329MK20040329RO20040329SI20040329CA200200132420020827enWO20030185792003030620031020040714200429