(19)
(11) EP 1 436 329 A1

(12)

(43) Date of publication:
14.07.2004 Bulletin 2004/29

(21) Application number: 02775937.2

(22) Date of filing: 20.09.2002
(51) International Patent Classification (IPC)7C07K 16/00, C07K 16/28, C12N 15/00, A61K 39/395
(86) International application number:
PCT/US2002/030086
(87) International publication number:
WO 2003/025019 (27.03.2003 Gazette 2003/13)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 20.09.2001 US 323537 P
20.09.2001 US 323544 P
13.05.2002 US 379994 P

(71) Applicant: ALEXION PHARMACEUTICALS, INC.
Cheshire, CT 06410 (US)

(72) Inventors:
  • BOWDISH, Katherine, S.
    Del Mark, CA 92014 (US)
  • FREDERICKSON, Shana
    Solana Beach, CA 92075 (US)
  • KRETZ-ROMMEL, Anke
    San Diego, CA 92116 (US)

(74) Representative: Soames, Candida Jane 
D Young & Co,21 New Fetter Lane
London EC4A 1DA
London EC4A 1DA (GB)

   


(54) ANTI-PDGF ANTIBODIES AND METHODS FOR PRODUCING ENGINEERED ANTIBODIES