(19)

(11)

EP 1 436 584 A1

(12)

(43) Date of publication: 14.07.2004 Bulletin 2004/29 (21) Application number: 02770624.1 (22) Date of filing: 21.10.2002

(51) International Patent Classification (IPC)7: G01N 1/28, A61B 10/00, B01L 3/00, G01N 33/483 (86) International application number: PCT/US2002/033459 (87) International publication number: WO 2003/034035 (24.04.2003 Gazette 2003/17)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 19.10.2001 US 330092 P 15.04.2002 US 372080 P 15.04.2002 US 122151 (71) Applicant: MonoGen, Inc. Vernon Hills, IL 60061-1360 (US)	(72) Inventors: PRESSMAN, Norman, J. Glencoe, IL 60022 (US) MAYER, William, J. South Barrington, IL 60010 (US) (74) Representative: Evens, Paul Jonathan et al Maguire Boss,5 Crown Street St. Ives,Cambridge PE27 5EB St. Ives,Cambridge PE27 5EB (GB)