(19)

(11)

EP 1 439 818 A1

(12)

(43) Date of publication: 28.07.2004 Bulletin 2004/31 (21) Application number: 02774744.3 (22) Date of filing: 23.10.2002

(51) International Patent Classification (IPC)7: A61K 9/00, A61K 31/195, A61K 33/10, A61K 31/70 (86) International application number: PCT/EP2002/011843 (87) International publication number: WO 2003/035027 (01.05.2003 Gazette 2003/18)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 23.10.2001 DE 10152169 (71) Applicant: Boehringer Ingelheim International GmbH 55216 Ingelheim am Rhein (DE)	(72) Inventors: MAROCCHI, Michael, David DELTA, British Columbia V4K 2S7 (CA) CAPPELLINI, Claudia CH-6948 PORZA (CH) GIANESELLO, Valter CH-6945 ORIGLIO (CH)