(19)
(11) EP 1 440 159 A2

(12)

(88) Date of publication A3:
25.03.2004

(43) Date of publication:
28.07.2004 Bulletin 2004/31

(21) Application number: 02802562.5

(22) Date of filing: 31.10.2002
(51) International Patent Classification (IPC)7C12P 19/34, C12Q 1/68
(86) International application number:
PCT/US2002/035251
(87) International publication number:
WO 2003/055443 (10.07.2003 Gazette 2003/28)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 31.10.2001 US 334852 P

(71) Applicants:
  • Alcon, Inc.
    6331 Hünenberg (CH)
  • UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER,Office of Research
    Fort Worth, TX 76107 (US)

(72) Inventors:
  • CLARK, Abbot, F.
    Arlington, TX 76017 (US)
  • WORDINGER, Robert, J.
    Euless, TX 76017 (US)

(74) Representative: Moore, Barry 
Hanna, Moore & Curley,11 Mespil Road
Dublin 4
Dublin 4 (IE)

   


(54) BONE MORPHOGENIC PROTEINS (BMP), BMP RECEPTORS AND BMP BINDING PROTEINS AND THEIR USE IN THE DIAGNOSIS AND TREATMENT OF GLAUCOMA