(19)
(11) EP 1 444 353 A2

(12)

(88) Date of publication A3:
06.05.2004

(43) Date of publication:
11.08.2004 Bulletin 2004/33

(21) Application number: 00938260.7

(22) Date of filing: 12.06.2000
(51) International Patent Classification (IPC)7C12N 15/869
(86) International application number:
PCT/US2000/016050
(87) International publication number:
WO 2000/077167 (21.12.2000 Gazette 2000/51)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 11.06.1999 US 138963 P

(71) Applicants:
  • THE GENERAL HOSPITAL CORPORATION
    Boston, MA 02114 (US)
  • The Regents of The University of California
    Oakland, CA 94607-5200 (US)

(72) Inventors:
  • SPEAR, Matthew,A
    San Diego, CA 92122 (US)
  • BREAKEFIELD, Xandra
    Newton Center, MA 02159 (US)

(74) Representative: Chapman, Paul William et al
Kilburn & Strode,20 Red Lion Street
London WC1R 4PJ
London WC1R 4PJ (GB)


(56) References cited: : 
   
       


    (54) HERPES SIMPLEX VIRUS AMPLICON VECTOR TARGETING SYSTEM AND METHOD OF USING SAME