(19)

(11)

EP 1 446 147 A1

(12)

(43) Date of publication: 18.08.2004 Bulletin 2004/34 (21) Application number: 02785096.5 (22) Date of filing: 08.11.2002

(51) International Patent Classification (IPC)7: A61K 38/36, A61K 38/48, A61K 31/195, A61P 7/04 (86) International application number: PCT/DK2002/000751 (87) International publication number: WO 2003/039581 (15.05.2003 Gazette 2003/20)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 09.11.2001 DK 200101672 27.11.2001 US 333648 P (71) Applicant: Novo Nordisk Health Care AG 8050 Zürich (CH)	(72) Inventor: ROEJKJAER, Rasmus DK-2820 Gentofte (DK) (74) Representative: Nilsson, Karin Norvin et al Novo Nordisk A/S,Corporate Patents,Novo Allé 2880 Bagsvaerd 2880 Bagsvaerd (DK)