ATBECHDEDKESFRGBGRITLILUNLSEMCPTIE......FI....CY..TRBGCZEE....SK....................................*JDIM360 Ver 2.15 (14 Jul 2008) - 2999001/01451338CORRECTED EUROPEAN PATENT SPECIFICATIONB8B120120502W172deBibliographieenBibliographyfrBibliographieEP02789453.4200211052004060420070402enenen332849 P20011105US2012050220121820040901200436201110192011422011060120120502201218C12P 21/08 20060101AFI20030520BHEP C07K 16/00 20060101ALI20030520BHEP G01N 33/53 20060101ALI20030520BHEP C12M 3/00 20060101ALI20030520BHEP deREKOMBINANTE ANTIKÖRPER ZUM NACHWEIS UND ZUR NEUTRALISIERUNG VON MILZBRANDTOXINenRECOMBINANT ANTIBODIES FOR THE DETECTION AND NEUTRALIZATION OF ANTHRAX TOXINfrANTICORPS RECOMBINES SERVANT A LA DETECTION ET A LA NEUTRALISATION DE LA TOXINE DE L'ANTHRAXWO-A1-99/36569US-A- 5 601 823US-B1- 6 329 156MAYNARD JENNIFER ET AL: "Affinity maturation of anti-anthrax toxin SCFV" ABSTRACTS OF PAPERS AMERICAN CHEMICAL SOCIETY, vol. 216, no. 1-3, 1998, page BIOT 212, XP009069346 & 216TH NATIONAL MEETING OF THE AMERICAN CHEMICAL SOCIETY; BOSTON, MASSACHUSETTS, USA; AUGUST 23-27, 1998 ISSN: 0065-7727CIRINO NICK M ET AL: "Disruption of anthrax toxin binding with the use of human antibodies and competitive inhibitors" INFECTION AND IMMUNITY, AMERICAN SOCIETY FOR MICROBIOLOGY. WASHINGTON, US, vol. 67, no. 6, June 1999 (1999-06), pages 2957-2963, XP002185394 ISSN: 0019-9567MAYNARD JENNIFER A ET AL: "Protection against anthrax toxin by recombinant antibody fragments correlates with antigen affinity" NATURE BIOTECHNOLOGY, vol. 20, no. 6, June 2002 (2002-06), pages 597-601, XP002390004 ISSN: 1087-0156KNAPPIK A ET AL: "Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides" JOURNAL OF MOLECULAR BIOLOGY, LONDON, GB, vol. 296, no. 1, 11 February 2000 (2000-02-11), pages 57-86, XP004461525 ISSN: 0022-2836CASTILLO J ET AL: "T7 displayed peptides as targets for selecting peptide specific scFvs from M13 scFv display libraries" JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 257, no. 1-2, 1 November 2001 (2001-11-01), pages 117-122, XP004311943 ISSN: 0022-1759WALORY J ET AL: "Comparison of four serological methods for the detection of diphtheria anti-toxin antibody" JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 245, no. 1-2, 1 November 2000 (2000-11-01), pages 55-65, XP004218808 ISSN: 0022-1759STEMMER W P C: "Rapid evolution of a protein in vitro by DNA shuffling" NATURE, NATURE PUBLISHING GROUP, LONDON, GB, vol. 370, 4 August 1994 (1994-08-04), pages 389-391, XP002082182 ISSN: 0028-0836LITTLE S.F. ET AL.: 'Passive protection by polyclonal antibodies against bacillus anthracis infection in guinea pigs' INFECTION AND IMMUNITY vol. 65, no. 12, December 1997, pages 5171 - 5175, XP002959464LITTLE S.F. ET AL.: 'Production and characterization of monoclonal antibodies to the protective antigen component of Bacillus anthracis toxin' INFECTION AND IMMUNITY vol. 56, no. 7, July 1988, pages 1807 - 1813, XP002959465TURNBULL P.C.B. ET AL.: 'Antibodies to anthrax toxin in humans and guinea pigs and their relevance to protective immunity' MED. MICROBIOL. IMMUNOL. vol. 177, no. 5, 1988, pages 293 - 303, XP00295946620061124GEORGIOU, George The University of Texas at AustinDepartment of Chemical Engineering, CPE BuildingAustin, TX 78712USIVERSON, B. L., The University of Texas at AustinDepartment of Chemistry, Welch Hall 5.320Austin, TX 78712USMAYNARD, J. A., The University of Texas at AustinDepartment of Chemical Engineering, MBB 3.310Austin, TX 78712USBOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM100089315FUL-132 EP201 West Seventh StreetAustin, TX 78701USDehmel, Albrecht100037386Dehmel & Bettenhausen Patentanwälte Herzogspitalstrasse 1180331 MünchenDEATBEBGCHCYCZDEDKEEESFIFRGBGRIEITLILUMCNLPTSESKTRUS200203556720021105enWO20030403842003051520032020040901200436