(19)
(11) EP 1 453 522 A1

(12)

(43) Date of publication:
08.09.2004 Bulletin 2004/37

(21) Application number: 01998044.0

(22) Date of filing: 13.12.2001
(51) International Patent Classification (IPC)7A61K 31/585, A61P 5/42
(86) International application number:
PCT/US2001/048419
(87) International publication number:
WO 2003/051372 (26.06.2003 Gazette 2003/26)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(71) Applicant: Pharmacia Corporation
St. Louis,Missouri 63006 (US)

(72) Inventors:
  • WILLIAMS, Gordon, H.
    Belmont, MA 02478 (US)
  • FUNDER, John, W.
    Victoria, Australia 3181 (AU)
  • GARTHWAITE, Susan, M.
    Evanston, IL 60202 (US)
  • RONIKER, Barbara
    Chicago, IL 60610 (US)
  • FEDDE, Kenton, N.
    Webster Groves, MO 63119 (US)
  • ROCHA, Ricardo
    Gurnee, IL 60031 (US)

(74) Representative: Wood, David John 
Pfizer LimitedEuropean Patents Department,Ramsgate Road,
Sandwich,Kent CT13 9NJ
Sandwich,Kent CT13 9NJ (GB)

   


(54) METHODS FOR TREATMENT OR PROPHYLAXIS OF ALDOSTERONE-MEDIATED PATHOGENIC EFFECTGS IN A SUBJECT USING AN EPOXY-STEROIDAL ALDOSTERONE ANTAGONIST