(19)
(11) EP 1 455 812 A2

(12)

(88) Date of publication A3:
31.07.2003

(43) Date of publication:
15.09.2004 Bulletin 2004/38

(21) Application number: 02784651.8

(22) Date of filing: 26.11.2002
(51) International Patent Classification (IPC)7A61K 38/19, A61K 39/395, C07K 14/52, C07K 16/28
(86) International application number:
PCT/US2002/038164
(87) International publication number:
WO 2003/045978 (05.06.2003 Gazette 2003/23)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 26.11.2001 US 333355 P

(71) Applicant: CHIRON CORPORATION
EmeryvilleCalifornia 94608-2916 (US)

(72) Inventors:
  • MASUOKA, Lorianne, K.
    Oakland, CA 94608 (US)
  • KWAN, Min, F.
    Emeryville, CA 94605 (US)

(74) Representative: Marshall, Cameron John et al
Carpmaels & Ransford43-45 Bloomsbury Square
London WC1A 2RA
London WC1A 2RA (GB)

   


(54) ANTAGONIST ANTI-CD40 MONOCLONAL ANTIBODY THERAPY FOR MULTIPLE SCLEROSIS TREATMENT