(19)

(11)

EP 1 456 642 A1

(12)

(43) Date of publication: 15.09.2004 Bulletin 2004/38 (21) Application number: 99964935.3 (22) Date of filing: 22.12.1999

(51) International Patent Classification (IPC)7: G01N 33/00, B01L 11/00, C12Q 1/68 (86) International application number: PCT/SG1999/000149 (87) International publication number: WO 2001/046688 (28.06.2001 Gazette 2001/26)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (71) Applicant: Applera Corporation Foster City, CA 94404 (US)	(72) Inventor: SHIN, Hon Siu Singapore 520112 (SG) (74) Representative: Carter, Stephen John et al OLSWANG90 High Holborn London WC1V 6XX London WC1V 6XX (GB)