(19)
(11) EP 1 456 670 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
27.04.2011 Bulletin 2011/17

(45) Mention of the grant of the patent:
15.07.2009 Bulletin 2009/29

(21) Application number: 02758547.0

(22) Date of filing: 22.08.2002
(51) International Patent Classification (IPC): 
G01N 33/92(2006.01)
C12Q 1/25(2006.01)
A61K 49/00(2006.01)
 G01N 33/569(2006.01)
G01N 33/68(2006.01)
(86) International application number:
PCT/GB2002/003863
(87) International publication number:
WO 2003/019198 (06.03.2003 Gazette 2003/10)

(54)

METHODS RELATING TO TREATMENT OF ATHEROSCLEROSIS

VERFAHREN BETREFFEND DIE BEHANDLUNG VON ATHEROSKLEROSE

PROCEDES CONCERNANT LE TRAITEMENT DE L'ATHEROSCLEROSE

(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR

(30) Priority: 22.08.2001 GB 0120428
18.09.2001 US 323127 P
06.02.2002 GB 0202774
06.02.2002 US 355655 P
27.02.2002 GB 0204611
16.07.2002 GB 0216530
18.07.2002 GB 0216755

(43) Date of publication of application:
15.09.2004 Bulletin 2004/38

(73) Proprietor: Cambridge Theranostics Ltd.
Cambridge CB4 0TP (GB)

(72) Inventor:
  • PETYAEV, Ivan
    Cambridge, Cambridgeshire CB1 3UE (GB)

(74) Representative: Sutcliffe, Nicholas Robert et al
Mewburn Ellis LLP 33 Gutter Lane
London EC2V 8AS
London EC2V 8AS (GB)


(56) References cited: : 
   
  • PETYAEV I M: "Extraction of anti-lipoprotein abzymes from human atherosclerotic lesion: Antibodies which bind and oxidise LDL" JOURNAL OF SUBMICROSCOPIC CYTOLOGY AND PATHOLOGY, vol. 32, no. 3, July 2000 (2000-07), page 477 XP009020233 XIth International Vascular Biology Meeting;Geneva, Switzerland; September 05-09, 2000 ISSN: 1122-9497
  • PETYAEV IVAN ET AL: "Superoxide dismutase activity of antibodies purified from the human arteries and atherosclerotic lesions" BIOCHEMICAL SOCIETY TRANSACTIONS, vol. 26, no. 1, February 1998 (1998-02), page S43 XP009019809 663rd Meeting of the Biochemical Society;Galway, Ireland; September 3-5, 1997 ISSN: 0300-5127
  • SOBAL GRAZYNA ET AL: "Influence of acetylsalicylic acid on oxidation of native and glycated low-density lipoprotein" LIFE SCIENCES, vol. 66, no. 20, 7 April 2000 (2000-04-07), pages 1987-1998, XP002260794 ISSN: 0024-3205
  • STEER KEITH A ET AL: "Aspirin protects low density lipoprotein from oxidative modification" HEART (LONDON), vol. 77, no. 4, 1997, pages 333-337, XP009020522 ISSN: 1355-6037
  • GURFINKEL ENRIQUE P ET AL: "Emerging role of antibiotics in atherosclerosis" AMERICAN HEART JOURNAL, vol. 138, no. 5 PART 2, November 1999 (1999-11), pages S537-S538, XP009020528 ISSN: 0002-8703
  • KALAYOGLU MURAT V ET AL: "Cellular oxidation of low-density lipoprotein by Chlamydia pneumoniae" JOURNAL OF INFECTIOUS DISEASES, vol. 180, no. 3, September 1999 (1999-09), pages 780-790, XP002260125 ISSN: 0022-1899
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).