(19)

(11)

EP 1 458 868 A2

(12)

(88) Date of publication A3: 29.04.2004 (43) Date of publication: 22.09.2004 Bulletin 2004/39 (21) Application number: 02787309.0 (22) Date of filing: 24.12.2002

(51) International Patent Classification (IPC)7: C12N 15/52, C12N 15/31, C12N 1/21, C07K 14/36, C07K 16/12, C07K 16/40 (86) International application number: PCT/CA2002/002021 (87) International publication number: WO 2003/060127 (24.07.2003 Gazette 2003/30)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE SI TR Designated Extension States: AL LT LV MK RO (30) Priority: 26.12.2001 US 342133 P 17.04.2002 US 372789 P (71) Applicant: Ecopia Biosciences Inc. Saint-Laurent,Québec H4S 2A1 (CA)	(72) Inventors: FARNET, Chris, M. Outremont, Québec H2V 3S3 (CA) STAFFA, Alfredo Saint-Laurent, Québec H4L 5M5 (CA) ZAZOPOULOS, Emmanuel Montreal, Québec H2Y 2M8 (CA) (74) Representative: VOSSIUS & PARTNER  Siebertstrasse 4 81675 München 81675 München (DE)