(19)

(11)

EP 1 465 619 A1

(12)

(43) Date of publication: 13.10.2004 Bulletin 2004/42 (21) Application number: 03702427.0 (22) Date of filing: 13.01.2003

(51) International Patent Classification (IPC)7: A61K 31/353, A61K 31/37, A61K 31/138, A61K 31/4535, A61P 19/02, A61P 19/10 (86) International application number: PCT/EP2003/000241 (87) International publication number: WO 2003/063859 (07.08.2003 Gazette 2003/32)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR Designated Extension States: AL LT LV MK RO (30) Priority: 14.01.2002 GB 0200743 14.01.2002 US 348730 P 25.04.2002 GB 0209495 (71) Applicant: Nordic Bioscience A/S 2730 Herlev (DK)	(72) Inventors: CHRISTIANSEN, Claus DK-2950 Vedbaek (DK) CHRISTGAU, Stephan DK-2820 Gentofte (DK) (74) Representative: Smart, Peter John  W.H. BECK, GREENER & CO7 Stone BuildingsLincoln's Inn London WC2A 3SZ London WC2A 3SZ (GB)