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(11)

EP 1 465 645 A1

(12)

(43) Date of publication: 13.10.2004 Bulletin 2004/42 (21) Application number: 01274887.7 (22) Date of filing: 05.12.2001

(51) International Patent Classification (IPC)7: A61K 35/78, A61K 31/365, A61P 35/00 (86) International application number: PCT/IN2001/000214 (87) International publication number: WO 2003/047608 (12.06.2003 Gazette 2003/24)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (71) Applicant: Council of Scientific andIndustrial Research New Delhi 110 001 (IN)

(72) Inventors: RAO, Janaswamy Madhusudana 500 007 Andhra Pradesh (IN) SRINIVAS, Pullela Venkata 500 007 Andhra Pradesh (IN) YADAV, Jhillu Singh 500 007 Andhra Pradesh (IN) RAGHAVAN, Kondapuram Vijaya 500 007 Andhra Pradesh (IN) SAXENA, A. K. 180 001 Jammu (IN) SHANMUGAVEL, M. 180 001 Jammu (IN) KAMPASI, Himani 180 001 Jammu (IN) QAZI, Gulam Nabi 180 001 Jammu (IN) (74) Representative: Portal, Gérard et al Cabinet Beau de Loménie158, rue de l'Université 75340 Paris Cédex 07 75340 Paris Cédex 07 (FR)