(19)

(11)

EP 1 467 987 A1

(12)

(43) Date of publication: 20.10.2004 Bulletin 2004/43 (21) Application number: 03748985.3 (22) Date of filing: 28.07.2003

(51) International Patent Classification (IPC)7: C07D 401/12 (86) International application number: PCT/US2003/023588 (87) International publication number: WO 2004/011455 (05.02.2004 Gazette 2004/06)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 26.07.2002 US 398686 P (71) Applicant: TEVA PHARMACEUTICAL INDUSTRIES LTD. 49131 Petah Tiqva (IL)	(72) Inventor: FINKELSTEIN, Nina 46290 Herzliya (IL) (74) Representative: Bradley, Josephine Mary et al D. Young & Co.,21 New Fetter Lane London EC4A 1DA London EC4A 1DA (GB)