FLUORO SUBSTITUTED CYCLOALKANOINDOLES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS - Patent 1470107

(19)

(11)

EP 1 470 107 A2

(12)

(88)	Date of publication A3:
	04.12.2003

(43)	Date of publication:
	27.10.2004 Bulletin 2004/44

(21)	Application number: 03700740.8

(22)	Date of filing: 22.01.2003

(51)	International Patent Classification (IPC)⁷: C07D 209/80, A61K 31/403, A61P 43/00, C07D 209/88

(86)	International application number:
	PCT/CA2003/000084

(87)	International publication number:
	WO 2003/062200 (31.07.2003 Gazette 2003/31)

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR
	Designated Extension States:
	AL LT LV MK RO

(30)

Priority:

24.01.2002 US 351384 P

(71)	Applicant: MERCK FROSST CANADA & CO.
	Kirkland, Quebec H9H 3L1 (CA)

(72)	Inventors:
	BERTHELETTE, Carl Kirkland, Québec H9H 3L1 (CA) LACHANCE, Nicolas Kirkland, Québec H9H 3L1 (CA) LI, Lianhai Kirkland, Québec H9H 3L1 (CA) STURINO, Claudio Kirkland, Québec H9H 3L1 (CA) WANG, Zhaoyin Kirkland, Québec H9H 3L1 (CA)

(74)	Representative: Buchan, Gavin MacNicol et al
	Merck & Co., Inc.,European Patent Department,Terlings Park,Eastwick Road Harlow,Essex CM20 2QR Harlow,Essex CM20 2QR (GB)

(54)	FLUORO SUBSTITUTED CYCLOALKANOINDOLES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS