ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESILTLVFIROMKCYAL..................................................*JDIM360 Ver 2.15 (14 Jul 2008) - 2999001/01471926CORRECTED EUROPEAN PATENT SPECIFICATIONB8B120110921W172deBibliographieenBibliographyfrBibliographieEP00941220.6200006012002010220060103enenen137060 P19990601US176993 P20000119US2011092120113820041103200445201012082010492010052620110921201138A61K 38/00 20060101AFI20040901BHEP deZUSAMMENSETZUNGEN UND VERFAHREN ZUR THERAPEUTISCHEN ANWENDUNG EINER MIT DEM GEN ATONAL ASSOZIIERTEN SEQUENZenCOMPOSITIONS AND METHODS FOR THE THERAPEUTIC USE OF AN ATONAL-ASSOCIATED SEQUENCEfrCOMPOSITIONS ET METHODES POUR L'UTILISATION THERAPEUTIQUE D'UNE SEQUENCE ASSOCIEE AU GENE ATONALBEN-ARIE N. ET AL.: 'Abnormal cerebellar development in mice lacking the murine homolog of the drosophila proneural gene atonal' AMERICAN J. HUMAN GENETICS vol. 59, no. 4, SUPPL., 1996, page A46, ABSTRACT NO. 232, XP002934142BEN-ARIE N. ET AL.: 'Math1 is essential for genesis of cerebellar granule neurons' NATURE vol. 390, 13 November 1997, pages 169 - 172, XP002934141SUN Y. ET AL.: 'Transcriptional regulation of atonal during development of the drosophila peripheral nervous system' DEVELOPMENT vol. 125, 1998, pages 3731 - 3740, XP002934140SABATE O. ET AL.: 'Adenovirus for neurodegenerative diseases: In vivo strategies and ex vivo gene therapy using human neural progenitors' CLINICAL NEUROSCIENCE vol. 3, 1996, pages 317 - 321, XP002934139WILLIAMS D.P. ET AL.: 'Structure/function analysis of interleukin-2-toxin (DAB486-IL-2), fragment B sequences required for the delivery of fragment A to the cytosol of target cells' J. BIOL. CHEM. vol. 265, no. 20, 15 July 1990, pages 11885 - 11887, XP002934138CHIEN C.-T. ET AL.: 'Neuronal type information encoded in the basic-helix-loop-helix domain of proneural genes' PROC. NATL. ACAD. SCI. USA vol. 93, November 1996, pages 13239 - 13244, XP002934137SCHWARZE S.R. ET AL.: 'In vivo protein transduction: delivery of a biologically active protein into the mouse' SCIENCE vol. 285, 03 September 1999, pages 1569 - 1572, XP002934136VERMA I.M. ET AL.: 'Gene therapy-promises, problems and prospects' NATURE vol. 389, 18 September 1997, pages 239 - 242, XP002934135LEDLEY F.D.: 'Pharmaceutical approach to somatic gene therapy' PHARMACEUTICAL RESEARCH vol. 13, no. 11, November 1996, pages 1595 - 1614, XP0029341342002061910010154.2232519820100922ZOGHBI, Huda, Y.6618 SewaneeHouston, TX 77005USBELLEN, Hugo3411 Mt. VernonHouston, TX 77006USBERMINGHAM, Nessanc/o Bio Equity Capital, LLC 75 Arlington St., Suite 500Boston MA 02116USHASSAN, Bassem1422 Richmond Avenue 3053Houston, TX 77006USBEN-ARIE, Nissim, Dept. of Cell and Animal BiologyHebrew University of Jerusalem, Givat-Ram91904 JerusalemILBAYLOR COLLEGE OF MEDICINE100084608N84270GCWOne Baylor PlazaHouston, TX 77030USWoods, Geoffrey Corlett100023317J.A. Kemp & Co. 14 South SquareGray's Inn London WC1R 5JJGBATBECHCYDEDKESFIFRGBGRIEITLILUMCNLPTSEAL20020102LT20020102LV20020102MK20020102RO20020102SI20020102US200001541020000601enWO200007376420001207200049