(19)
(11) EP 1 472 515 A2

(12)

(88) Date of publication A3:
26.02.2004

(43) Date of publication:
03.11.2004 Bulletin 2004/45

(21) Application number: 03710857.8

(22) Date of filing: 05.02.2003
(51) International Patent Classification (IPC)7G01N 3/48, G01N 33/483, G01N 33/487, G01N 33/50, G01N 33/53, G01N 33/58
(86) International application number:
PCT/US2003/003389
(87) International publication number:
WO 2003/066813 (14.08.2003 Gazette 2003/33)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR
Designated Extension States:
AL LT LV MK RO

(30) Priority: 06.02.2002 US 354824 P
20.02.2002 US 358217 P
20.02.2002 US 358189 P
20.02.2002 US 358126 P
21.02.2002 US 358995 P
21.02.2002 US 358756 P
21.02.2002 US 358765 P
25.02.2002 US 359531 P
26.02.2002 US 360222 P
26.02.2002 US 360224 P
26.02.2002 US 360167 P
26.02.2002 US 360166 P

(71) Applicant: Exelixis, Inc.
South San Francisco, CA 94083-0511 (US)

(72) Inventors:
  • BRACE, Arthur
    Foster City, CA 94404 (US)
  • ELIARES, agnes, V.
    San Francisco, CA 94133 (US)
  • FERGUSON, Kimberly, Carr
    San Francisco, CA 94116 (US)
  • SEIDEL-DUGEN, Cynthia
    Benicia, CA 94510 (US)
  • MAPA, Felipa, A.
    San Francisco, CA 94110 (US)
  • RUHRMUND, Donald
    Berkeley, CA 94703 (US)
  • WU, Jianfeng
    Daly City, CA 94015 (US)

(74) Representative: Main, Malcolm Charles 
Murgitroyd & CompanyScotland House165-169 Scotland Street
Glasgow G5 8PL
Glasgow G5 8PL (GB)

   


(54) MINRs AS MODIFIERS FO INSULIN RECEPTOR SIGNALING AND METHODS OF USE