PRODUCTION OF HUMAN ANTIBODIES IN IMMUNODEFICIENT, NON-HUMAN, MAMMALIAN HOSTS - Patent 1474682

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EP 1 474 682 A2

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(88)	Date of publication A3:
	29.07.2004

(43)	Date of publication:
	10.11.2004 Bulletin 2004/46

(21)	Application number: 03710962.6

(22)	Date of filing: 10.02.2003

(51)	International Patent Classification (IPC)⁷: G01N 33/00, C12P 21/00, A01K 67/00, C07K 16/00, C12N 5/06

(86)	International application number:
	PCT/US2003/003999

(87)	International publication number:
	WO 2003/068915 (21.08.2003 Gazette 2003/34)

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR
	Designated Extension States:
	AL LT LV MK RO

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Priority:

11.02.2002 US 356082 P

(71)	Applicant: ALEXION PHARMACEUTICALS, INC.
	Cheshire, CT 06410 (US)

(72)	Inventors:
	KRETZ-ROMMEL, Anke San Diego, CA 92116 (US) XIN, Hong La Jolla, CA 92037 (US)

(74)	Representative: Soames, Candida Jane
	D Young & Co,21 New Fetter Lane London EC4A 1DA London EC4A 1DA (GB)

(54)	PRODUCTION OF HUMAN ANTIBODIES IN IMMUNODEFICIENT, NON-HUMAN, MAMMALIAN HOSTS