(19)
(11) EP 1 476 157 A1

(12)

(43) Date of publication:
17.11.2004 Bulletin 2004/47

(21) Application number: 03700974.3

(22) Date of filing: 03.02.2003
(51) International Patent Classification (IPC)7A61K 31/455, A61P 29/00, A61P 11/00, C07D 213/82
(86) International application number:
PCT/IB2003/000377
(87) International publication number:
WO 2003/068232 (21.08.2003 Gazette 2003/34)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR
Designated Extension States:
AL LT LV MK RO

(30) Priority: 11.02.2002 GB 0203193

(71) Applicants:
  • Pfizer Limited
    Sandwich,Kent CT13 9NJ (GB)

    GB 
  • PFIZER INC.
    New York, N.Y. 10017 (US)

    AT BE BG CH CY CZ DE DK EE ES FI FR GR HU IE IT LU MC NL LI 

(72) Inventor:
  • Magee, Thomas Victor
    Groton, CT 06340 (US)

(74) Representative: Laurent, Claire 
PFIZER PGRDEuropean Pharma Patent Dept.23/25 Avenue du Docteur Lannelongue
75668 Paris Cedex 14
75668 Paris Cedex 14 (FR)

   


(54) NICOTINAMIDE DERIVATIVES USEFUL AS PDE4 INHIBITORS