(19)
(11) EP 1 476 431 A1

(12)

(43) Date of publication:
17.11.2004 Bulletin 2004/47

(21) Application number: 03742812.5

(22) Date of filing: 19.02.2003
(51) International Patent Classification (IPC)7C07D 231/54, C07D 487/04, C07D 495/04, A61K 31/416, A61P 35/02
(86) International application number:
PCT/US2003/004844
(87) International publication number:
WO 2003/070706 (28.08.2003 Gazette 2003/35)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR
Designated Extension States:
AL LT LV MK RO

(30) Priority: 19.02.2002 US 357960 P

(71) Applicant: Pharmacia Corporation
St. Louis, MO 63006 (US)

(72) Inventors:
  • XU, Xiangdong
    Gurnee, IL 60031 (US)
  • CLARE, Michael
    Skokie, IL 60077 (US)
  • LENNON, Patrick
    Webster Groves, MO 63119 (US)
  • METZ, Suzanne
    Chesterfield, MO 63017 (US)
  • VAZQUEZ, Michael
    Ballwin, MO 63021 (US)
  • WEIER, Richard, M.
    Lake Bluff, IL 60044 (US)
  • WOLFSON, Serge, G.
    Chesterfield, MO 63017 (US)

(74) Representative: Bridle, Andrew Barry 
Pfizer LimitedUK Patent DepartmentRamsgate Road
Sandwich, Kent CT13 9NJ
Sandwich, Kent CT13 9NJ (GB)

   


(54) TRICYCLIC PYRAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATION