(19)

(11)

EP 1 476 759 A2

(12)

(88) Date of publication A3: 11.03.2004 (43) Date of publication: 17.11.2004 Bulletin 2004/47 (21) Application number: 03739491.3 (22) Date of filing: 13.02.2003

(51) International Patent Classification (IPC)7: G01N 33/68 (86) International application number: PCT/EP2003/001462 (87) International publication number: WO 2003/069346 (21.08.2003 Gazette 2003/34)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR Designated Extension States: AL LT LV MK RO (30) Priority: 18.02.2002 GB 0203768 (71) Applicant: Universite de Geneve 1211 Genève 4 (CH)	(72) Inventors: HOCHSTRASSER, Denis, Francois CH-1245 Geneva (CH) SANCHEZ, Jean-Charles CH-1208 Geneva (CH) GUILLAUME, Elisabeth F-01220 Divonne les Bains (FR) ALLARD, Laure F-74240 Gaillard (FR) (74) Representative: Lucas, Brian Ronald  Lucas & Co.135 Westhall Road Warlingham,Surrey CR6 9HJ Warlingham,Surrey CR6 9HJ (GB)