CRYSTAL STRUCTURES OF JNK-INHIBITOR COMPLEXES AND BINDING POCKETS THEREOF - Patent 1476840

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EP 1 476 840 A2

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(88)	Date of publication A3:
	27.11.2003

(43)	Date of publication:
	17.11.2004 Bulletin 2004/47

(21)	Application number: 03708827.5

(22)	Date of filing: 10.01.2003

(51)	International Patent Classification (IPC)⁷: G06F 19/00, A01N 61/00

(86)	International application number:
	PCT/US2003/000899

(87)	International publication number:
	WO 2003/060102 (24.07.2003 Gazette 2003/30)

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR
	Designated Extension States:
	AL LT LV MK RO

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Priority:

11.01.2002 US 348002 P

(71)	Applicant: VERTEX PHARMACEUTICALS INCORPORATED
	Cambridge, MA 02139-4242 (US)

(72)	Inventor:
	XIE, Xiaoling Cambridge ,MA 02139 (US)

(74)	Representative: VOSSIUS & PARTNER
	Siebertstrasse 4 81675 München 81675 München (DE)

(54)	CRYSTAL STRUCTURES OF JNK-INHIBITOR COMPLEXES AND BINDING POCKETS THEREOF