(19) |
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(11) |
EP 1 477 476 A8 |
(12) |
CORRECTED EUROPEAN PATENT APPLICATION |
(48) |
Corrigendum issued on: |
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22.06.2005 Bulletin 2005/25 |
(43) |
Date of publication: |
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17.11.2004 Bulletin 2004/47 |
(22) |
Date of filing: 16.05.2003 |
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(84) |
Designated Contracting States: |
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AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR |
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Designated Extension States: |
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AL LT LV MK |
(71) |
Applicant: Organisation de Synthese Mondiale Orsymonde |
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94700 Maisons Alfort (FR) |
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(72) |
Inventor: |
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- Rose, Sébastien
60190 Arsy (FR)
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(74) |
Representative: Bernasconi, Jean Raymond et al |
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c/o Cabinet Lavoix, 2, Place d'Estienne d'Orves 75441 Paris Cedex 09 75441 Paris Cedex 09 (FR) |
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(54) |
Modafinil synthesis process |
(57) The invention relates to a process for preparing modafinil having a defined granulometry
which comprises the steps of:
- a) preparing a solution of DMSAM ;
- b) contacting the solution obtained with NH3 at a predetermined temperature and a
predetermined stirring; and
- c) isolating the modafinil formed,
wherein said temperature and said stirring are predetermined in order to obtain said
defined granulometry.