(19)
(11) EP 1 480 950 A1

(12)

(43) Date of publication:
01.12.2004 Bulletin 2004/49

(21) Application number: 03713610.8

(22) Date of filing: 19.02.2003
(51) International Patent Classification (IPC)7C07D 207/327
(86) International application number:
PCT/US2003/005384
(87) International publication number:
WO 2003/070702 (28.08.2003 Gazette 2003/35)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR
Designated Extension States:
AL LT LV MK RO

(30) Priority: 15.02.2002 US 357181 P
12.11.2002 US 425325 P

(71) Applicant: TEVA PHARMACEUTICAL INDUSTRIES LTD.
49131 Petah Tiqva (IL)

(72) Inventors:
  • TESSLER, Limor
    Natanya 42380 (IL)
  • ARONHIME, Judith
    Rehovot 76217 (IL)
  • LIFSHITZ-LIRON, Revital
    Herzlia, 46322 (IL)
  • MAIDAN-HANOCH, Dalia
    Kfar Yona (IL)
  • HASSON, Nir
    Meitar 85025 (IL)

(74) Representative: Bradley, Josephine Mary et al
D Young & Co120 Holborn
London EC1N 2DY
London EC1N 2DY (GB)

   


(54) NOVEL CRYSTAL FORMS OF ATORVASTATIN HEMI-CALCIUM AND PROCESSES FOR THEIR PREPARATION, AS WELL AS NOVEL PROCESSES FOR PREPARING ATORVASTATIN HEMI-CALCIUM FORMS I, VIII AND IX