(19)
(11) EP 1 480 977 A2

(12)

(88) Date of publication A3:
04.12.2003

(43) Date of publication:
01.12.2004 Bulletin 2004/49

(21) Application number: 03742704.4

(22) Date of filing: 10.02.2003
(51) International Patent Classification (IPC)7C07D 453/02, C07D 471/08, C07D 487/08, C07D 209/94, A61K 31/40, A61P 25/00
(86) International application number:
PCT/US2003/002673
(87) International publication number:
WO 2003/070728 (28.08.2003 Gazette 2003/35)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR
Designated Extension States:
AL LT LV MK RO

(30) Priority: 15.02.2002 US 357472 P
15.02.2002 US 357465 P
20.02.2002 US 358083 P

(71) Applicant: PHARMACIA & UPJOHN COMPANY
Kalamazoo,Michigan 49001 (US)

(72) Inventors:
  • WALKER, Daniel, P.
    Kalamazoo, MI 49009 (US)
  • PIOTROWSKI, David, W.
    Portage, MI 49024 (US)
  • JACOBSEN, Jon, E.
    Richland, MI 49083 (US)
  • ACKER, Brad, A.
    Kalamazoo, MI 49009 (US)
  • MYERS, Jason, K.
    Kalamazoo, MI 49001 (US)
  • GROPPI, Vincent, E., Jr.
    Kalamazoo, MI 49006 (US)

(74) Representative: Rutt, Jason Edward 
Pfizer LimitedEuropean Patents Department,Ramsgate Road
Sandwich, Kent CT13 9NJ
Sandwich, Kent CT13 9NJ (GB)

   


(54) SUBSTITUTED ARYL COMPOUNDS FOR TREATMENT OF DISEASE