(19)

(11)

EP 1 482 960 A2

(12)

(88) Date of publication A3: 23.09.2004 (43) Date of publication: 08.12.2004 Bulletin 2004/50 (21) Application number: 02782326.9 (22) Date of filing: 19.11.2002

(51) International Patent Classification (IPC)7: A61K 38/00 (86) International application number: PCT/US2002/037136 (87) International publication number: WO 2003/043518 (30.05.2003 Gazette 2003/22)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 20.11.2001 US 331665 P 27.02.2002 US 360736 P 27.06.2002 US 186168 (71) Applicant: DMI Biosciences, Inc. Englewood, CO 80110-3948 (US)	(72) Inventor: BAR-OR, David Englewood, CO 80110 (US) (74) Representative: Murphy, Colm Damien  Urquhart-Dykes & Lord LLP,30 Welbeck Street London W1G 8ER London W1G 8ER (GB)