(19)

(11)

EP 1 487 414 A2

(12)

(88) Date of publication A3: 15.07.2004 (43) Date of publication: 22.12.2004 Bulletin 2004/52 (21) Application number: 03714005.0 (22) Date of filing: 07.03.2003

(51) International Patent Classification (IPC)7: A61K 9/14, A61K 9/22, A61K 9/24, A61K 9/28, A61K 9/48 (86) International application number: PCT/US2003/007118 (87) International publication number: WO 2003/075852 (18.09.2003 Gazette 2003/38)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 07.03.2002 US 92811 07.03.2002 US 92854 07.03.2002 US 92858 07.03.2002 US 93214 07.03.2002 US 93321 (71) Applicant: Advancis Pharmaceutical Corporation Gaithersburg, MD 20878 (US)	(72) Inventors: RUDNIC, Edward, M. North Potomac, MD 20878 (US) ISBISTER, James, D. Potomac, MD 20878 (US) TREACY, Jr., Donald, J. Arnold, MD 21012 (US) WASSINK, Sandra, E. Frederick, MD 21704 (US) (74) Representative: Walcher, Armin, Dipl.-Ing. Dr.  Louis, Pöhlau, Lohrentz Postfach 3055 90014 Nürnberg 90014 Nürnberg (DE)