(19)

(11)

EP 1 487 504 A1

(12)

(43) Date of publication: 22.12.2004 Bulletin 2004/52 (21) Application number: 03719312.5 (22) Date of filing: 19.02.2003

(51) International Patent Classification (IPC)7: A61L 9/013, A61L 9/14, A61L 2/18 (86) International application number: PCT/US2003/004940 (87) International publication number: WO 2003/070286 (28.08.2003 Gazette 2003/35)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR Designated Extension States: AL LT LV MK RO (30) Priority: 19.02.2002 US 358089 P (71) Applicant: EDEN RESEARCH PLC Chipping Norton OX7 3DG (GB)	(72) Inventors: FRANKLIN, Lanny, U. Atlanta, GA 30342-2558 (US) PIMENTEL, Julio, L. Buford, GA 30519 (US) (74) Representative: Ouzman, Beverley Nicola Claire et al Murgitroyd and Company,165-169 Scotland Street Glasgow G5 8PL Glasgow G5 8PL (GB)