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(11)

EP 1 490 348 A1

(12)

(43) Date of publication: 29.12.2004 Bulletin 2004/53 (21) Application number: 03744800.8 (22) Date of filing: 12.03.2003

(51) International Patent Classification (IPC)7: C07D 305/14, C07F 7/18, G01N 33/48 (86) International application number: PCT/EP2003/002634 (87) International publication number: WO 2003/080587 (02.10.2003 Gazette 2003/40)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 21.03.2002 EP 02076113 (71) Applicant: Pharmacia Italia S.p.A. 20152 Milano (IT)	(72) Inventors: GIRIBONE, Danilo I-20147 Milan (IT) FONTANA, Erminia I-20014 Nerviano (MI) (IT) (74) Representative: Tesch, Rudolf, Dr. et al c/o Pfizer GmbH,Arzneimittelwerk GödeckeMooswaldallee 1 79090 Freiburg 79090 Freiburg (DE)