(19)

(11)

EP 1 495 124 A2

(12)

(88) Date of publication A3: 06.05.2004 (43) Date of publication: 12.01.2005 Bulletin 2005/02 (21) Application number: 03722503.4 (22) Date of filing: 17.04.2003

(51) International Patent Classification (IPC)7: C12N 15/12, C12N 15/62, A61K 47/48, C07K 5/103, C07K 19/00, C07K 14/47, A61K 38/17, C07K 5/10, A61K 41/00 (86) International application number: PCT/EP2003/004039 (87) International publication number: WO 2003/086470 (23.10.2003 Gazette 2003/43)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 17.04.2002 EP 02008199 12.07.2002 EP 02015499 (71) Applicant: Deutsches KrebsforschungszentrumStiftung des öffentlichen Rechts 69120 Heidelberg (DE)	(72) Inventors: DEBATIN, Klaus, Michael 89075 Ulm (DE) FULDA, Simone 89075 Ulm (DE) (74) Representative: Huhn, Michael, Dr.  Isenbruck Bösl HörschlerWichmann HuhnPatentanwälteTheodor-Heuss-Anlage 12 68165 Mannheim 68165 Mannheim (DE)