(19)
(11) EP 1 496 931 A1

(12)

(43) Date of publication:
19.01.2005 Bulletin 2005/03

(21) Application number: 03747047.3

(22) Date of filing: 18.04.2003
(51) International Patent Classification (IPC)7A61K 38/16, C07K 14/705
(86) International application number:
PCT/US2003/012356
(87) International publication number:
WO 2003/088991 (30.10.2003 Gazette 2003/44)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated Extension States:
AL LT LV MK

(30) Priority: 19.04.2002 US 373852 P
30.08.2002 US 407246 P

(71) Applicant: Bristol-Myers Squibb Company
Princeton, NJ 08543-4000 (US)

(72) Inventors:
  • COHEN, Robert
    Newton, PA 18940 (US)
  • CARR, Suzette
    Hopewell, NJ 08525 (US)
  • HAGERTY, David
    Pennington, NJ 08534 (US)
  • PEACH, Robert, J.
    San Diego, CA 92129 (US)
  • BECKER, Jean-Claude
    Princeton, NJ 08540 (US)

(74) Representative: Reitstötter - Kinzebach & Partner (GbR) 
PatentanwälteSternwartstrasse 4
81679 München
81679 München (DE)

   


(54) METHODS FOR TREATING AN AUTOIMMUNE DISEASE USING A SOLUBLE CTLA4 MOLECULE AND A DMARD OR NSAID