(19)

(11)

EP 1 499 303 A2

(12)

(88) Date of publication A3: 18.12.2003 (43) Date of publication: 26.01.2005 Bulletin 2005/04 (21) Application number: 03717010.7 (22) Date of filing: 09.04.2003

(51) International Patent Classification (IPC)7: A61K 9/48, A61K 9/52, A61K 9/64 (86) International application number: PCT/US2003/010816 (87) International publication number: WO 2003/086267 (23.10.2003 Gazette 2003/43)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 10.04.2002 US 371448 P 18.02.2003 US 369427 18.02.2003 US 368951 18.02.2003 US 369244 18.02.2003 US 369247 (71) Applicant: Miller, Fred H. Tampa, FL 33611 (US)	(72) Inventor: MILLER, Fred, H. Tampa, FL 33611 (US) (74) Representative: Thornton, Neil  Reddie & Grose,16 Theobalds Road London WC1X 8PL London WC1X 8PL (GB)