(19)
(11) EP 1 501 522 A2

(12)

(88) Date of publication A3:
11.03.2004

(43) Date of publication:
02.02.2005 Bulletin 2005/05

(21) Application number: 03750067.5

(22) Date of filing: 06.05.2003
(51) International Patent Classification (IPC)7: A61K 31/74
(86) International application number:
PCT/US2003/014087
(87) International publication number:
WO 2003/094929 (20.11.2003 Gazette 2003/47)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated Extension States:
AL LT LV MK

(30) Priority: 06.05.2002 US 378529 P
06.05.2002 WO PCT/US02/14402

(71) Applicant: University of Utah Research Foundation
Salt Lake City,Utah 84108 (US)

(72) Inventors:
  • PRESTWICH, Glenn, D.
    Salt Lake City, UT 84108 (US)
  • ZHANG, Lurong
    Bethseda, MD 20817 (US)

(74) Representative: Helbing, Jörg, Dr. Dipl.-Chem. et al
Patentanwältevon Kreisler-Selting-Werner,Postfach 10 22 41
50462 Köln
50462 Köln (DE)

   


(54) PREBLOCKING WITH NON-HA GAGS INCREASES EFFECTIVENESS OF HA CONJUGATED ANTICANCER AGENTS