(19)
(11) EP 1 503 801 A2

(12)

(88) Date of publication A3:
08.01.2004

(43) Date of publication:
09.02.2005 Bulletin 2005/06

(21) Application number: 03727872.8

(22) Date of filing: 28.04.2003
(51) International Patent Classification (IPC)7: A61K 48/00, C12N 15/12, C12N 15/79, C12N 15/16, C12N 15/18, A61P 11/00, G01N 33/74
(86) International application number:
PCT/IB2003/002371
(87) International publication number:
WO 2003/091387 (06.11.2003 Gazette 2003/45)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

(30) Priority: 26.04.2002 AU PS193502
02.07.2002 US 188184

(71) Applicant: Ferguson, Ian A.
Crafers West, S.A. 5152 (AU)

(72) Inventors:
  • Ferguson, Ian A.
    Crafers West, SA 5152 (AU)
  • TANI, Hiroaki
    Eden Hills, SA 5050 (AU)

(74) Representative: Dzieglewska, Hanna Eva 
Frank B. Dehn & Co.,European Patent Attorneys,179 Queen Victoria Street
London EC4V 4EL
London EC4V 4EL (GB)

   


(54) NON-INVASIVE DELIVERY OF POLYPEPTIDES THROUGH THE BLOOD-BRAIN BARRIER, AND IN VIVO SELECTION OF ENDOCYTOTIC LIGANDS