(19)

(11)

EP 1 509 206 A1

(12)

(43) Date of publication: 02.03.2005 Bulletin 2005/09 (21) Application number: 03736570.7 (22) Date of filing: 28.05.2003

(51) International Patent Classification (IPC)7: A61K 9/14, A61K 9/16 (86) International application number: PCT/US2003/014545 (87) International publication number: WO 2003/101429 (11.12.2003 Gazette 2003/50)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 31.05.2002 US 157921 (71) Applicant: Materials Modification, Inc. Fairfax, VA 22031 (US)	(72) Inventors: KOTHA, sanjay Falls Church, VA 22044 (US) SUDARSHAN, Tirumalai, S. Vienna, VA 22182 (US) (74) Representative: Marlow, Nicholas Simon et al Reddie & Grose16, Theobalds Road London WC1X 8PL London WC1X 8PL (GB)