(19)
(11) EP 1 509 505 A2

(12)

(88) Date of publication A3:
08.01.2004

(43) Date of publication:
02.03.2005 Bulletin 2005/09

(21) Application number: 03705889.8

(22) Date of filing: 23.01.2003
(51) International Patent Classification (IPC)7: C07D 231/16, C07D 231/14, C07D 231/12, C07D 401/12, C07D 409/04, A61K 31/415, A61K 31/4155, A61P 7/02, A61P 9/10
(86) International application number:
PCT/US2003/002059
(87) International publication number:
WO 2003/062206 (31.07.2003 Gazette 2003/31)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR
Designated Extension States:
AL LT LV MK RO

(30) Priority: 23.01.2002 US 386198 P
05.06.2002 US 386384 P
05.08.2002 US 401467 P

(71) Applicant: Arena Pharmaceuticals, Inc.
San Diego, CA 92121 (US)

(72) Inventors:
  • TEEGARDEN, Bradley
    San Diego, CA 92131 (US)
  • DROUET, Keith
    San Diego, CA 92121 (US)
  • JAYAKUMAR, Honnappa
    San Diego, CA 92129 (US)
  • THOMSEN, William
    Del Mar, CA 92014 (US)
  • MAFFUID, Paul
    Carlsbad, CA 92009 (US)
  • ELWELL, Katie
    Solana Beach, CA 92075 (US)
  • FOSTER, Richard
    Cornwall EX23 0AX (GB)
  • LAWLESS, Michael
    St. Charles, MO 63303 (US)
  • LIU, Qian
    Ballwin, MO 63011 (US)
  • SMITH, Julian
    Exeter,Devon EX4 2JJ (GB)
  • FEICHTINGER, Konrad
    San Diego, CA 92103 (US)

(74) Representative: Eisenführ, Speiser & Partner 
Patentanwälte RechtsanwältePostfach 10 60 78
28060 Bremen
28060 Bremen (DE)

   


(54) SMALL MOLECULE MODULATORS OF THE 5−HT2A SEROTONIN RECEPTOR USEFUL FOR THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO