(19)

(11)

EP 1 509 594 A1

(12)

(43) Date of publication: 02.03.2005 Bulletin 2005/09 (21) Application number: 03722082.9 (22) Date of filing: 30.05.2003

(51) International Patent Classification (IPC)7: C12M 1/42, C12N 5/12, C12N 5/16, C12N 5/28, C12N 13/00, A61K 48/00, A61K 35/54 (86) International application number: PCT/AU2003/000660 (87) International publication number: WO 2003/102125 (11.12.2003 Gazette 2003/50)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 31.05.2002 US 384882 P 07.06.2002 US 387284 P 19.06.2002 AU PS307802 05.09.2002 AU 2002951223 05.09.2002 AU 2002951222 (71) Applicant: Apollo Life Sciences Pty Ltd. Beaconsfield,New South Wales 2015 (AU)	(72) Inventors: WILLS, Ivan, Nicholas Tempe, New South Wales 2044 (AU) MONAGHAN, David Robert James Botany, New South Wales 2019 (AU) (74) Representative: Skone James, Robert Edmund  GILL JENNINGS & EVERY,Broadgate House,7 Eldon Street London EC2M 7LH London EC2M 7LH (GB)